A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Por um escritor misterioso
Last updated 20 setembro 2024
Researchers from the group Mitochondrial regulation of cell death and steatohepatitis have revealed a new role for acid ceramidase (ACDase) in experimental models and in patients with NPC through the regulation of STARD1 and its impact on mitochondrial function.
Niemann–Pick type C disease: cellular pathology and pharmacotherapy - Wheeler - 2020 - Journal of Neurochemistry - Wiley Online Library
NPC1 - Wikipedia
Sterol regulation of the expression and transcription of the
Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells
STARD1 and NPC1 expression as pathological markers associated with astrogliosis in post-mortem brains from patients with Alzheimer's disease and Down syndrome
NPC1 enables cholesterol mobilization during long‐term potentiation that can be restored in Niemann–Pick disease type C by CYP46A1 activation
The pathogenesis of Niemann–Pick type C disease: a role for autophagy?, Expert Reviews in Molecular Medicine
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
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