Biomedicines, Free Full-Text
Por um escritor misterioso
Last updated 11 março 2025

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic of coronavirus disease in 2019 (COVID-19). Genome surveillance is a key method to track the spread of SARS-CoV-2 variants. Genetic diversity and evolution of SARS-CoV-2 were analyzed based on 260,673 whole-genome sequences, which were sampled from 62 countries between 24 December 2019 and 12 January 2021. We found that amino acid (AA) substitutions were observed in all SARS-CoV-2 proteins, and the top six proteins with the highest substitution rates were ORF10, nucleocapsid, ORF3a, spike glycoprotein, RNA-dependent RNA polymerase, and ORF8. Among 25,629 amino acid substitutions at 8484 polymorphic sites across the coding region of the SARS-CoV-2 genome, the D614G (93.88%) variant in spike and the P323L (93.74%) variant in RNA-dependent RNA polymerase were the dominant variants on six continents. As of January 2021, the genomic sequences of SARS-CoV-2 could be divided into at least 12 different clades. Distributions of SARS-CoV-2 clades were featured with temporal and geographical dynamics on six continents. Overall, this large-scale analysis provides a detailed mapping of SARS-CoV-2 variants in different geographic areas at different time points, highlighting the importance of evaluating highly prevalent variants in the development of SARS-CoV-2 antiviral drugs and vaccines.

Biomedicines, Free Full-Text

BioMedicine, Journal
Inflammation is a multistep process triggered by a variety of causes

Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination

Glycocalyx Research and Studies using GlycoCheck Technology

Gut microbiota and its metabolites in depression: from pathogenesis to treatment - eBioMedicine

Generate: Biomedicines - Fonts In Use

Biomolecules and Biomedicine

Biomedicines, Free Full-Text

Biomedicines (ISSN 2227-9059, IF: 6.081) Questionnaire: Participate in the 10th Anniversary Online Survey Now
Recomendado para você
-
Pokemon Let's Go Type Chart Type Weaknesses and Strengths11 março 2025
-
Daydreaming Ban on X: I decided to update my favorite Pokemon for11 março 2025
-
Types - Pokemon Heart Gold and Soul Silver Guide - IGN11 março 2025
-
Pokemon Type Chart11 março 2025
-
Pokemon presentations11 março 2025
-
Why was the Ice-type removed from Generation IV of Pokémon games? - Quora11 março 2025
-
Pokemon Crystal Version Type Chart Map for Game Boy Color by Llamaman2 - GameFAQs11 março 2025
-
Future of Monotype Run Articles11 março 2025
-
Ability Chart image - Entodrive - ModDB11 março 2025
-
pokemon type chart if game freak knew how to make good games : r11 março 2025
você pode gostar
-
Evil Dead: The Game Review - Prepare to Have Your Free Time11 março 2025
-
Gordon's Special Dry London Gin Bottle 37.5% Vol 1L - Tesco Groceries11 março 2025
-
See Ghostface Creeping People Out For Scream VI's Viral Marketing Campaign11 março 2025
-
Assassin's Creed Origins Adds Free Update And Premium DLC This Month - GameSpot11 março 2025
-
Autism Creature Tbh Creature GIF - Discover & Share GIFs - Tenor11 março 2025
-
᩠͡♡ ↬ 𝖲𝖺𝗌𝖺𝗄𝗂 & 𝖬𝗂𝗒𝖺𝗇𝗈 𝗂𝖼𝗈𝗇 𓂅᜔࣪11 março 2025
-
Throne and Liberty Closed Beta Test Footage Now up on : r/MMORPG11 março 2025
-
O espírito santo e a divindade11 março 2025
-
Pés De Jogadores De Futebol Antes De Iniciar Uma Partida Imagem de11 março 2025
-
Jogo Ludo Master no Jogos 36011 março 2025