Biomedicines, Free Full-Text
Por um escritor misterioso
Last updated 05 abril 2025

Alpha-synuclein’s role in diseases termed “synucleinopathies”, including Parkinson’s disease, has been well-documented. However, after over 25 years of research, we still do not fully understand the alpha-synuclein protein and its role in disease. In vitro cellular models are some of the most powerful tools that researchers have at their disposal to understand protein function. Advantages include good control over experimental conditions, the possibility for high throughput, and fewer ethical issues when compared to animal models or the attainment of human samples. On the flip side, their major disadvantages are their questionable relevance and lack of a “whole-brain” environment when it comes to modeling human diseases, such as is the case of neurodegenerative disorders. Although now, with the advent of pluripotent stem cells and the ability to create minibrains in a dish, this is changing. With this review, we aim to wade through the recent alpha-synuclein literature to discuss how different cell culture setups (immortalized cell lines, primary neurons, human induced pluripotent stem cells (hiPSCs), blood–brain barrier models, and brain organoids) can help us understand aggregation pathology in Parkinson’s and other synucleinopathies.

An overview on nanoparticles used in biomedicine and their

Free Radicals Brain Injury - Colaboratory

License Key File Scavenger Version 4.1 - Colaboratory

Cellular and molecular biomarkers of long COVID: a scoping review

SARS-CoV-2 Initiates Programmed Cell Death in Platelets

Changes in nanomechanical properties of single neuroblastoma cells

Generate: Biomedicines - Fonts In Use

Serial Para Internet Manager 6.21 - Colaboratory

Decoding the Patterns of Self and Nonself by the Innate Immune

Biomedicines An Open Access Journal from MDPI

Biomedicines, Free Full-Text

Medical viruses: diagnostic techniques, Virology Journal
Recomendado para você
-
Kelly Godoy Coelho Correspondente Dinâmico05 abril 2025
-
510kRwERo1L._CLa, 597,500, 51k1tROyz9L.jpg,51zWZl8ZIhL.jpg05 abril 2025
-
longa noite sombria05 abril 2025
-
Aprovados - Cursos preparatórios para concursos05 abril 2025
-
Monalisa dos Reis Aguiar05 abril 2025
-
Algorithms Illuminated - 4 book series05 abril 2025
-
FRAPA 202305 abril 2025
-
Where the Bird Sings Best05 abril 2025
-
Forests, Free Full-Text05 abril 2025
-
Scientific publications 2023 SIB Swiss Institute of Bioinformatics05 abril 2025
você pode gostar
-
Vikings – 2×04 – Eye for an Eye05 abril 2025
-
Sonic EXE - Download Free 3D model by cleverdamontoutube (@cleverdamontoutube) [2f29797]05 abril 2025
-
Are Pokémon GO Shiny Rates Boosted During Spotlight Hours05 abril 2025
-
That One and Only Hu Tao Team, Now Complete Genshin Impact05 abril 2025
-
COMO CONSEGUIR O CÓDIGO PARA SE REGISTRAR - GTA SAMP BRASIL05 abril 2025
-
aphmau playing uno|TikTok Search05 abril 2025
-
Conheça Ella Freya, modelo responsável por dar vida para Ashley em05 abril 2025
-
Cat or Ice Cream? by cookiecrayon05 abril 2025
-
NEW LEGENDARY SWORD Showcase on A One Piece Game05 abril 2025
-
roronoa tami on X: MBTI DOS PERSONAGENS DE MO DAO ZU SHI - a05 abril 2025