Biomedicines, Free Full-Text

Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated in the pathogenesis of various brain diseases, including neurodegenerative disorders, stroke, and psychiatric illnesses. This review paper provides a comprehensive overview of the intricate relationship between mitochondria and brain disease, focusing on the underlying pathological mechanisms and exploring potential therapeutic opportunities. The review covers key topics such as mitochondrial DNA mutations, impaired oxidative phosphorylation, mitochondrial dynamics, calcium dysregulation, and reactive oxygen species generation in the context of brain disease. Additionally, it discusses emerging strategies targeting mitochondrial dysfunction, including mitochondrial protective agents, metabolic modulators, and gene therapy approaches. By critically analysing the existing literature and recent advancements, this review aims to enhance our understanding of the multifaceted role of mitochondria in brain disease and shed light on novel therapeutic interventions.

Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination

Maternal exposure to ambient black carbon particles and their presence in maternal and fetal circulation and organs: an analysis of two independent population-based observational studies - The Lancet Planetary Health

Povyk sloužit hlavní, důležitý exosomes metastases and the miracle of cancer stem cell markers spirála Darebák požehnání

NMR in Biomedicine - Wiley Online Library

Nanobodies as a powerful platform for biomedicine: Trends in Molecular Medicine

Patients With COVID-19 Have Elevated Levels of Circulating Extracellular Vesicle Tissue Factor Activity That Is Associated With Severity and Mortality—Brief Report

Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles

SARS-CoV-2 Initiates Programmed Cell Death in Platelets

The Ageless Generation: How Advances in Biomedicine Will Transform the Global Economy: Zhavoronkov, Alex: 9780230342200: : Books

Daru Duru Pk Song - Colaboratory

Articles by Sajjad Ahmad's Profile, Freelance Journalist

Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers