Biomedicines, Free Full-Text
Por um escritor misterioso
Last updated 24 março 2025

Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a global health threat, especially with the continuous development of antibiotic resistance. As an opportunistic pathogen, MRSA infections have a high mortality rate worldwide. Although classically described as an extracellular pathogen, many studies have shown over the past decades that MRSA also has an intracellular aspect to its infectious cycle, which has been observed in vitro in both non-professional as well as professional phagocytes. In vivo, MRSA has been shown to establish an intracellular niche in liver Kupffer cells upon bloodstream infection. The staphylococci have evolved various evasion strategies to survive the antimicrobial environment of phagolysosomes and use these compartments to hide from immune cells and antibiotics. Ultimately, the host cells get overwhelmed by replicating bacteria, leading to cell lysis and bacterial dissemination. In this review, we describe the different intracellular aspects of MRSA infection and briefly mention S. aureus evasion strategies. We discuss how this intracellular niche of bacteria may assist in antibiotic tolerance development, and lastly, we describe various new antibacterial strategies that target the intracellular bacterial niche.

New insights and options into the mechanisms and effects of

Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination

Open Access Journal of Biomedical Science

Biomedicines, Free Full-Text

Biomedicines An Open Access Journal from MDPI
Boxplots for illustration of cell numbers in stimulated and

NMR in Biomedicine - Wiley Online Library
Molecular Biomedicine

Frontiers Clinical implementation of plasma cell-free
Recomendado para você
-
Staph Infection: Causes, Symptoms, Diagnosis & Treatment24 março 2025
-
Prevention and Control of a Staphylococcus aureus Infection24 março 2025
-
Are teicoplanin-non-susceptible Staphylococcus epidermidis strains increasing?24 março 2025
-
Staph infection-induced kidney disease may be linked to bacterial gene mutation24 março 2025
-
Staphylococcus aureus24 março 2025
-
Staphylococcus aureus seen under microscope after Gram's staining24 março 2025
-
Staphylococcus aureus: A Blemish on Skin Immunity: Cell Host & Microbe24 março 2025
-
Staphylococcus aureus Slide, w.m.: Science Lab Microbiology Supplies: : Industrial & Scientific24 março 2025
-
Compreendendo o Staphylococcus Aureus: Uma infecção bacteriana comum - GENE MEIDIKE24 março 2025
-
Antibiotics, Free Full-Text24 março 2025
você pode gostar
-
Jogo Infantil Jogos Educativos Para Crianças ATIVIDADE Quiz #424 março 2025
-
Shiny Zekrom by Phatmon on DeviantArt24 março 2025
-
Welcome to Demon-School, Iruma-kun (TV Series 2019–2023) - Episode24 março 2025
-
Digimon Adventure tri. Chapter 2 Determination Anime Trailer24 março 2025
-
Magical Girl ops is over and I'm sad but Jojo's lives on ! : r/Animemes24 março 2025
-
Brasil na versão anime : r/animebrasil24 março 2025
-
oshi no ko episode 3 dub|TikTok Search24 março 2025
-
Zamazenta V - SWSH077 - SWSH: Sword & Shield Promo Cards - Pokemon24 março 2025
-
Crop animated GIF24 março 2025
-
Rack Amsterdã Base Em Madeira Maciça Off White/madeira no Shoptime24 março 2025