Cancers, Free Full-Text

Imatinib became the standard treatment for chronic myeloid leukemia (CML) about 20 years ago, which was a major breakthrough in stabilizing the pathology and improving the quality of life of patients. However, the emergence of resistance to imatinib and other tyrosine kinase inhibitors leads researchers to characterize new therapeutic targets. Several studies have highlighted the role of histone deacetylase 6 (HDAC6) in various pathologies, including cancer. This protein effectively intervenes in cellular activities by its primarily cytoplasmic localization. In this review, we will discuss the molecular characteristics of the HDAC6 protein, as well as its overexpression in CML leukemic stem cells, which make it a promising therapeutic target for the treatment of CML.

National Comprehensive Cancer Network - Home

Cancer: Its Causes, Symptoms & Treatment, Giving the Results of Over Forty : Eli G Jones : Free Download, Borrow, and Streaming : Internet Archive

Download or order free information booklets

Cancer Cells: Types, How They Form, and Characteristics

Institutional Repository LinkOut: A New Full Text Access Feature in PubMed. NLM Technical Bulletin. 2017 Mar–Apr

Artificial intelligence-aided clinical annotation of a large multi-cancer genomic dataset

An Introduction to Human Cancers

Cancer Cells vs. Normal Cells: How Are They Different?

Detection of HPV-16 DNA by PCR in histologically cancer free lymph nodes from patients with cervical cancer. - Abstract - Europe PMC

What is secondary lung cancer?

Cancers, Free Full-Text

Cancer Survivor Photo Booth Props You Are My Hero Sign

Know the signs of cancer to catch it early

cancer free Poster for Sale by NiceShirtY