Methodology of the DCCSS later fatigue study: a model to

Background A debilitating late effect for childhood cancer survivors (CCS) is cancer-related fatigue (CRF). Little is known about the prevalence and risk factors of fatigue in this population. Here we describe the methodology of the Dutch Childhood Cancer Survivor Late Effect Study on fatigue (DCCSS LATER fatigue study). The aim of the DCCSS LATER fatigue study is to examine the prevalence of and factors associated with CRF, proposing a model which discerns predisposing, triggering, maintaining and moderating factors. Triggering factors are related to the cancer diagnosis and treatment during childhood and are thought to trigger fatigue symptoms. Maintaining factors are daily life- and psychosocial factors which may perpetuate fatigue once triggered. Moderating factors might influence the way fatigue symptoms express in individuals. Predisposing factors already existed before the diagnosis, such as genetic factors, and are thought to increase the vulnerability to develop fatigue. Methodology of the participant inclusion, data collection and planned analyses of the DCCSS LATER fatigue study are presented. Results Data of 1955 CCS and 455 siblings was collected. Analysis of the data is planned and we aim to start reporting the first results in 2022. Conclusion The DCCSS LATER fatigue study will provide information on the epidemiology of CRF and investigate the role of a broad range of associated factors in CCS. Insight in associated factors for fatigue in survivors experiencing severe and persistent fatigue may help identify individuals at risk for developing CRF and may aid in the development of interventions.

Cancers, Free Full-Text

Prevalence and risk factors of cancer‐related fatigue in childhood

Physical frailty deteriorates after a 5‐day dexamethasone course

Fatigue Damage Modeling of Structures and Materials

Methodology of the DCCSS later fatigue study: a model to

Flow diagram of publication identification and selection

Increased health‐related quality of life impairments of male and

Chronic fatigue in childhood cancer survivors is associated with

Kremer group - Prinses Máxima Centrum - Research

Prevalence and 95% Confidence Intervals of severe and chronic

PDF) Reliability and Validity of Turkish Versions of the Child