3D Printable Device for Automated Operant Conditioning in the Mouse
Por um escritor misterioso
Last updated 25 abril 2025

Operant conditioning (OC) is a classical paradigm and a standard technique used in experimental psychology in which animals learn to perform an action to achieve a reward. By using this paradigm, it is possible to extract learning curves and measure accurately reaction times (RTs). Both these measurements are proxy of cognitive capabilities and can be used to evaluate the effectiveness of therapeutic interventions in mouse models of disease. Here, we describe a fully 3D printable device that is able to perform OC on freely moving mice, while performing real-time tracking of the animal position. We successfully trained six mice, showing stereotyped learning curves that are highly reproducible across mice and reaching >70% of accuracy after 2 d of conditioning. Different products for OC are commercially available, though most of them do not provide customizable features and are relatively expensive. This data demonstrate that this system is a valuable alternative to available state-of-the-art commercial devices, representing a good balance between performance, cost, and versatility in its use.

An open-source device for measuring food intake and operant behavior in rodent home-cages

Open Source Toolkit

Behavior Apparatus - OpenBehavior

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Feeding Experimentation Device (FED): A flexible open-source device for measuring feeding behavior - ScienceDirect

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GitHub - raffaelemazziotti/oc_chamber: 3D printable operant conditioning chamber

Developing a Computer-Controlled Treat Dispenser for Canine Operant Conditioning - Journal of Open Hardware
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