Session 2: Expanding Frontiers of Genomic Medicine Enabled by Cost-Effective Next Generation Sequencing

Whole genome bisulfite sequencing (WGBS) enables a comprehensive analysis of an individual's DNA methylation profile and has the potential to enhance precision medicine initiatives by addressing both genetic and epigenetic factors simultaneously. Collecting DNA methylation data by WGBS offers valuable insights into disease origin, predisposition, and treatment response, potentially guiding therapeutic strategies. | Whole genome bisulfite sequencing (WGBS) enables a comprehensive analysis of an individual's DNA methylation profile and has the potential to enhance precision medicine initiatives by addressing both genetic and epigenetic factors simultaneously.

Frontiers A Study Protocol for Validation and Implementation of Whole- Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias

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