JCM, Free Full-Text
Por um escritor misterioso
Last updated 04 abril 2025

Overt hyperthyroidism (HT) during pregnancy is associated with a risk of maternal–fetal complications. Antithyroid drugs (ATD) have a potential risk for teratogenic effects and fetal–neonatal hypothyroidism. This study evaluated ATD treatment and thyroid function control during pregnancy, and pregnancy outcome in women with HT. Patients and methods: A retrospective analysis of 36 single fetus pregnancies in 29 consecutive women (median age 30.3 ± 4.7 years) with HT diagnosed before or during pregnancy; a control group of 39 healthy euthyroid pregnant women was used. Results: Twenty-six women had Graves’ disease (GD, 33 pregnancies), 1 had a hyperfunctioning autonomous nodule, and 2 had gestational transient thyrotoxicosis (GTT). Methimazole (MMI) was administered in 22 pregnancies (78.5%), Propylthiouracil (PTU) in 2 (7.1%), switch from MMI to PTU in 4 (14.2%), no treatment in 8 pregnancies (3 with subclinical HT, 5 euthyroid with previous GD remission before conception). In the 8 pregnancies of GD patients diagnosed during gestation or shortly before (<6 weeks), i.e., with fetal exposure to uncontrolled HT, there was 1 spontaneous abortion at 5 weeks (3.4% of all ATD-treated pregnancies), and 1 premature delivery at 32 weeks with neonatal death in 24 h (3.4%); 1 child had neonatal hyperthyroidism (3.3% of live children in GD women) and a small atrial sept defect (4% of live children in ATD treated women). In women treated more than 6 months until conception (20 pregnancies): (a) median ATD doses were lower than those in women diagnosed shortly before or during pregnancy; (b) ATD was withdrawn in 40% of pregnancies in trimester (T)1, all on MMI < 10 mg/day (relapse in 14.2%), and in up to 55% in T3; (c) TSH level was below normal in 37%, 35% and 22% of pregnancies in T1, T2 and T3 respectively; FT4 was increased in 5.8% (T1) and subnormal in 11.75% in T2 and T3; (d) no fetal birth defects were recorded; one fetal death due to a true umbilical cord knot was registered. Mean birth weight was similar in both ATD-treated and control groups. Hyperthyroidism relapsed postpartum in 83% of GD patients (at median 3 ± 2.6 months). Conclusion: In hyperthyroid women with long-term ATD treatment before conception, drugs could be withdrawn in T1 in 40% of them, the thyroid function control was better, and pregnancy and fetal complications were rarer, compared to women diagnosed during pregnancy. Frequent serum TSH and FT4 monitoring is needed to maintain optimal thyroid function during pregnancy.
Diseases of the skin: their constitutional nature and cure : Burnett, J. Compton (James Compton), 1840-1901? : Free Download, Borrow, and Streaming : Internet Archive

Dr. John Burroughs, Colorado Springs Oculoplastic Surgeon, Shares His Most Recent Publication. - Dr John Burroughs

gospel event january 2024|TikTok Search

Hire: Marshall JCM800 Head — Studiocare

Free JCM 800 Preset - Helix 3.70 Firmware!

Youth Sports & Fitness :: Joint Base Lewis-McChord :: US Army MWR

Joseph's Classic Market

Fet version of the JCM800

Marshall JCM800 2203X 100-watt Tube Head

Responsive Joomla template for Church, Charity, nonprofits - JA Charity

JCM, Free Full-Text

Events Calendar — Hope Evangelical Free Church

AmpliTube 5 CS - FREE amp simulation and guitar gear modeling software
Recomendado para você
-
Periodic table - Wikipedia04 abril 2025
-
A dagger M 37 for leaders, manufacturer M 7/36, E. & F. Hörster, Solingen Very good bright blade, the obverse with etched motto Blut und Ehre! (Blood and Honour!), the reverse etched04 abril 2025
-
FER, ANJ, and HERK1 receptors interact with RALF6, 7, 16, 36, and 3704 abril 2025
-
Solved Eu Eu - Euuuu Hb concentration 14 13.5 15.1 16.4 12.404 abril 2025
-
List of runner numbers04 abril 2025
-
A dagger M 37 for leaders, manufacturer M 7/36, E. & F. Hörster, Solingen Very good bright blade, the obverse with etched motto Blut und Ehre! (Blood and Honour!), the reverse etched04 abril 2025
-
Danish fungi as represented in the herbarium of ERostrup . If f 1 iH 1 lirifl ij 1 1 ,M Ill;II ii lil 1 J^ Fig. 29-30: Herpotrichia rubi Fuckel, hab.-p. asc.04 abril 2025
-
Big Blue Men's Basketball Picks Up Conference Win - Millikin University Athletics04 abril 2025
-
Wisconsin at Vicksburg: report of the Wisconsin-Vicksburg Monument Commission, including the story of the campaign and siege of Vicksburg in 1865 with especial reference to the activities therein of Wisconsin troops04 abril 2025
-
Williams' Covington and Newport directory [1898-1899] - City & County Directories - Digital Library04 abril 2025
você pode gostar
-
desenho de tartaruga desenho animado kawaii anime bonito para colorir 10504540 Vetor no Vecteezy04 abril 2025
-
Google Doodle Honours Jerry Lawson, The Inventor Of Video Game Cartridges04 abril 2025
-
Destiny 2 news: new DLC Rise of Iron will have its release September 2004 abril 2025
-
SHACHI: albums, songs, playlists04 abril 2025
-
SCP-1795 (The Star Womb) - Superhero Database04 abril 2025
-
Download & Play Temple Run 2 on PC with NoxPlayer - Appcenter04 abril 2025
-
number24 - Apple TV04 abril 2025
-
6º ANO - MATEMÁTICA - FRAÇÕES04 abril 2025
-
sped up edit ) Five Nights at Freddy's (Red Light Remix04 abril 2025
-
Cursos - PROJETUS Consultoria04 abril 2025