Nutrients, Free Full-Text
Por um escritor misterioso
Last updated 15 abril 2025

The mesencephalic trigeminal nucleus (Mes5) processes oral sensory–motor information, but its role in the control of energy balance remains unexplored. Here, using fluorescent in situ hybridization, we show that the Mes5 expresses the melanocortin-4 receptor. Consistent with MC4R activation in other areas of the brain, we found that Mes5 microinjection of the MC4R agonist melanotan-II (MTII) suppresses food intake and body weight in the mouse. Furthermore, NTS POMC-projecting neurons to the Mes5 can be chemogenetically activated to drive a suppression in food intake. Taken together, these findings highlight the Mes5 as a novel target of melanocortinergic control of food intake and body weight regulation, although elucidating the endogenous role of this circuit requires future study. While we observed the sufficiency of Mes5 MC4Rs for food intake and body weight suppression, these receptors do not appear to be necessary for food intake or body weight control. Collectively, the data presented here support the functional relevance of the NTS POMC to Mes5 projection pathway as a novel circuit that can be targeted to modulate food intake and body weight.

FDA Updates Nutrition Facts Panel - Free Template to Create Your Own Panels

Health effects of dietary risks in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 - The Lancet

Home Page: The American Journal of Clinical Nutrition

Nutrients, Free Full-Text

Nutrients, Free Full-Text

Nutrients An Open Access Journal from MDPI

Nutrients, Free Full-Text

Ssb Personal Interview Video Download - Colaboratory

Nutrients, Free Full-Text
Recomendado para você
-
oh so you are x name every y - Imgflip15 abril 2025
-
SCP-939 Poster for Sale by hanh5396515 abril 2025
-
Jennifer Swann - SCP Art: SCP-040 Evolution's Child15 abril 2025
-
Stolen SCP logo? : r/SCP15 abril 2025
-
08 - Goat - SCP-594 by SunnyClockwork on DeviantArt15 abril 2025
-
Where's your crown, King Nothing?, SCP Foundation15 abril 2025
-
🟥 THE BIG PAWNZY IS BACK ON KRUNKER BABY 🟥 ROAD TO 1K 🟥 !merch15 abril 2025
-
Dead Man´S Diary on XOne — price history, screenshots, discounts • USA15 abril 2025
-
SCP : Observer No Commentary #115 abril 2025
-
CLOSED] SCP genre, Builder portfolios - Portfolios - Developer Forum15 abril 2025
você pode gostar
-
Felpudo antideslizante de gato Floppa grande, felpudo Steampunk15 abril 2025
-
Virtua Fighter 5: Ultimate Showdown - Virtua Fighter 5 Ultimate Showdown DLC Trophy Guide •15 abril 2025
-
Boneco Sonic Preto Grande Collection Shadow - Super Size Figure15 abril 2025
-
WMF 9000s+ Bean to Cup Coffee Machine15 abril 2025
-
Mais alto fernandinho15 abril 2025
-
800+ Bo Brawl Stars Amino15 abril 2025
-
Se viene el tradicional Floripa Chess Open 2024!15 abril 2025
-
Invincible': Novidades da 2ª temporada serão divulgadas este mês - CinePOP15 abril 2025
-
MEQUINHO o xadrez de um grande mestre Caldeira, Adriano (Autor), Mecking, Henrique (Autor) Histórias, Xadrez, Jogos, mequinho xadrez Sinopse D - Carrefour15 abril 2025
-
Loja de Brinquedos e Disfarces online Centroxogo15 abril 2025