PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS
Por um escritor misterioso
Last updated 29 março 2025
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://d3i71xaburhd42.cloudfront.net/8f5d57c0faa9363000feb58f702a7c401e619ff5/4-Table2-1.png)
2 point BMS in association with CSF lactate dosage had the same sensitivity and negative predictive value, with increased specificity for diagnosis of bacterial meningitis when compared with 1-point BMS. ABSTRACT Objective: To evaluate Bacterial Meningitis Score (BMS) on its own and in association with Cerebrospinal Fluid (CSF) lactate dosage in order to distinguish bacterial from aseptic meningitis. Methods: Children diagnosed with meningitis at a tertiary hospital between January/2011 and December/2014 were selected. All data were obtained upon admission. BMS was applied and included: CSF Gram staining (2 points); CSF neutrophil count ≥1,000 cells/mm3 (1 point); CSF protein ≥80 mg/dL (1 point); peripheral blood neutrophil count ≥10,000 cells/mm3 (1 point) and seizures upon/before arrival (1 point). Cutoff value for CSF lactate was ≥30 mg/dL. Sensitivity, specificity and negative predictive value of several BMS cutoffs and BMS associated with high CSF lactate were evaluated for prediction of bacterial meningitis. Results: Among 439 eligible patients, 94 did not have all data available to complete the score, and 345 patients were included: 7 in bacterial meningitis group and 338 in aseptic meningitis group. As predictive factors of bacterial meningitis, BMS ≥1 had 100% sensitivity (95%CI 47.3-100), 64.2% specificity (58.8-100) and 100% negative predictive value (97.5-100); BMS ≥2 or BMS ≥1 associated with high CSF lactate also showed 100% sensitivity (47.3-100); but 98.5% specificity (96.6-99.5) and 100% negative predictive value (98.3-100). Conclusions: 2 point BMS in association with CSF lactate dosage had the same sensitivity and negative predictive value, with increased specificity for diagnosis of bacterial meningitis when compared with 1-point BMS.
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://www.aafp.org/content/dam/brand/aafp/pubs/afp/issues/2017/0901/p314-t7.gif)
Aseptic and Bacterial Meningitis: Evaluation, Treatment, and
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://d3i71xaburhd42.cloudfront.net/6b1913c12d3e42df4b0d3d04208619550be7a944/2-Figure1-1.png)
PDF] Performance of lactate in discriminating bacterial meningitis
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://d3i71xaburhd42.cloudfront.net/8f5d57c0faa9363000feb58f702a7c401e619ff5/2-Table1-1.png)
PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://ars.els-cdn.com/content/image/1-s2.0-S0163445316000244-gr1.jpg)
The UK joint specialist societies guideline on the diagnosis and
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://i1.rgstatic.net/publication/349039671_Cerebrospinal_fluid_changes_and_clinical_features_of_aseptic_meningitis_in_patients_with_Kawasaki_disease/links/60328c47299bf1cc26e06cb9/largepreview.png)
PDF) Cerebrospinal fluid changes and clinical features of aseptic
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://www.researchgate.net/publication/260429784/figure/tbl1/AS:669677810364448@1536675040782/CSF-lactate-concentration-in-children-with-bacterial-and-aseptic-meningitis.png)
CSF lactate concentration in children with bacterial and aseptic
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://www.mdpi.com/diagnostics/diagnostics-11-00846/article_deploy/html/images/diagnostics-11-00846-g002.png)
Diagnostics, Free Full-Text
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://www.mdpi.com/diagnostics/diagnostics-11-00846/article_deploy/html/images/diagnostics-11-00846-g001-550.jpg)
Diagnostics, Free Full-Text
![PDF] USE OF SCORE AND CEREBROSPINAL FLUID LACTATE DOSAGE IN DIFFERENTIAL DIAGNOSIS OF BACTERIAL AND ASEPTIC MENINGITIS](https://i1.rgstatic.net/publication/6421708_Cortisol_levels_in_cerebrospinal_fluid_correlate_with_severity_and_bacterial_origin_of_meningitis/links/00b495159e5cf04579000000/largepreview.png)
PDF) Cortisol levels in cerebrospinal fluid correlate with
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