Methodology of the DCCSS later fatigue study: a model to investigate chronic fatigue in long-term survivors of childhood cancer, BMC Medical Research Methodology
Por um escritor misterioso
Last updated 06 abril 2025

Background A debilitating late effect for childhood cancer survivors (CCS) is cancer-related fatigue (CRF). Little is known about the prevalence and risk factors of fatigue in this population. Here we describe the methodology of the Dutch Childhood Cancer Survivor Late Effect Study on fatigue (DCCSS LATER fatigue study). The aim of the DCCSS LATER fatigue study is to examine the prevalence of and factors associated with CRF, proposing a model which discerns predisposing, triggering, maintaining and moderating factors. Triggering factors are related to the cancer diagnosis and treatment during childhood and are thought to trigger fatigue symptoms. Maintaining factors are daily life- and psychosocial factors which may perpetuate fatigue once triggered. Moderating factors might influence the way fatigue symptoms express in individuals. Predisposing factors already existed before the diagnosis, such as genetic factors, and are thought to increase the vulnerability to develop fatigue. Methodology of the participant inclusion, data collection and planned analyses of the DCCSS LATER fatigue study are presented. Results Data of 1955 CCS and 455 siblings was collected. Analysis of the data is planned and we aim to start reporting the first results in 2022. Conclusion The DCCSS LATER fatigue study will provide information on the epidemiology of CRF and investigate the role of a broad range of associated factors in CCS. Insight in associated factors for fatigue in survivors experiencing severe and persistent fatigue may help identify individuals at risk for developing CRF and may aid in the development of interventions.

PDF) Chronic fatigue in childhood cancer survivors is associated

Auditory complications among childhood cancer survivors and health

PDF) The Dutch LATER physical outcomes set for self-reported data

The 'cognitive behavioural model' of chronic fatigue syndrome

Chronic fatigue in childhood cancer survivors is associated with

Cancer-related fatigue in childhood cancer survivors: A systematic

PDF) Longitudinal development of fatigue after treatment for

PDF) Recommendations for the surveillance of cancer-related

Venn diagram of prevalence and the symptom cluster of pain

BMC Medical Research Methodology 1/2021

Response Shift After Cognitive Behavioral Therapy Targeting Severe

Implementation of a clinical long-term follow-up database for
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