Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development
Por um escritor misterioso
Last updated 03 abril 2025


Structural overlays help to rationalize the SAR for 18 , 19 and 23

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. - Abstract - Europe PMC

Resolution achieved by automated reprocessing of data vs the resolution

Prioritization of Molecular Targets for Antimalarial Drug Discovery

Contacts between SC-58272 and Nmt1p.a, Contact distances (Å). The

Discovery of a Novel Class of Orally Active Trypanocidal N- Myristoyltransferase Inhibitors

Identification of and Structural Insights into Hit Compounds Targeting N- Myristoyltransferase for Cryptosporidium Drug Development

Plasmodium falciparum NMT substrates are involved in a variety of

PDF) Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani

Structure-guided design: (a) overlay of 3-OMe phenyl in 19 (PDB code

Cryptosporidiosis Drug Discovery: Opportunities and Challenges

Frontiers Mode of action studies confirm on-target engagement of lysyl-tRNA synthetase inhibitor and lead to new selection marker for Cryptosporidium
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