Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development
Por um escritor misterioso
Last updated 23 fevereiro 2025
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Structural overlays help to rationalize the SAR for 18 , 19 and 23
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N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. - Abstract - Europe PMC
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Resolution achieved by automated reprocessing of data vs the resolution
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Prioritization of Molecular Targets for Antimalarial Drug Discovery
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Contacts between SC-58272 and Nmt1p.a, Contact distances (Å). The
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Discovery of a Novel Class of Orally Active Trypanocidal N- Myristoyltransferase Inhibitors
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Identification of and Structural Insights into Hit Compounds Targeting N- Myristoyltransferase for Cryptosporidium Drug Development
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Plasmodium falciparum NMT substrates are involved in a variety of
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PDF) Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani
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Structure-guided design: (a) overlay of 3-OMe phenyl in 19 (PDB code
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Cryptosporidiosis Drug Discovery: Opportunities and Challenges
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Frontiers Mode of action studies confirm on-target engagement of lysyl-tRNA synthetase inhibitor and lead to new selection marker for Cryptosporidium
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