Frequency-specific neuromodulation of local and distant
Por um escritor misterioso
Last updated 11 março 2025

A growing literature has focused on the brain’s ability to augment processing in local regions by recruiting distant communities of neurons in response to neural decline or insult. In particular, both younger and older adult populations recruit bilateral prefrontal cortex (PFC) as a means of compensating for increasing neural effort to maintain successful cognitive function. However, it remains unclear how local changes in neural activity affect the recruitment of this adaptive mechanism. To address this problem, we combined graph theoretical measures from functional MRI (fMRI) with diffusion weighted imaging (DWI) and repetitive transcranial magnetic stimulation (rTMS) in order to resolve a central hypothesis: how do aged brains flexibly adapt to local changes in cortical activity? Specifically, we applied neuromodulation to increase or decrease local activity in a cortical region supporting successful memory encoding (left dorsolateral prefrontal cortex or DLPFC) using 5Hz or 1Hz rTMS, respectively. We then assessed a region’s local within-module degree (WMD), or the distributed between-module degree (BMD) between distant cortical communities. We predicted that (1) local stimulation-related deficits may be counteracted by boosting BMD between bilateral PFC, and that this effect should be (2) positively correlated with structural connectivity. Both predictions were confirmed; 5Hz rTMS increased local success-related activity and local increases in PFC connectivity, while 1Hz rTMS decreases local activity and triggered a more distributed pattern of bilateral PFC connectivity to compensate for this local inhibitory effect. These results provide an integrated, causal explanation for the network interactions associated with successful memory encoding in older adults.

Frontiers Implantable Pulse Generators for Deep Brain

Ultrasound Neuromodulation: A Review of Results, Mechanisms and

Organ-specific, multimodal, wireless optoelectronics for high

Magnetic nanomaterials for wireless thermal and mechanical

Low-frequency DBS does not induce HFO but evokes compound activity

Informing deep neural networks by multiscale principles of

Neuro-stack as a programmable closed-loop neuromodulation system a

Identifying spinal tracts transmitting distant effects of trans

Frequency-specific neuromodulation of local and distant

Frequency-Dependent Action of Neuromodulation

Frontiers Neuromodulation of Hippocampal-Prefrontal Cortical

Frontiers Remote electrical neuromodulation (REN) wearable

Modulation of deep neural circuits with sonogenetics

Frontiers Phase-locked closed-loop ultrasound stimulation
Recomendado para você
-
Brain Test Level 411 (NEW) Light up the birthday candles Answer11 março 2025
-
Lengkap Ada Video, Brain Test Level 411 Sang Ksatria Harus11 março 2025
-
Brain Teaser: 14+7-4=11 Can You Move 3 Matchsticks To Fix The11 março 2025
-
level 411 brain test11 março 2025
-
The 8 Cranial Bones Parts, Location & Function - Video & Lesson11 março 2025
-
The Mechanics of the Brain (Infographic)11 março 2025
-
Magnetism - Questions and Answers in MRI11 março 2025
-
Holiday Gift Guide for Loved Ones with Dementia - BrainTest11 março 2025
-
anoosha syed11 março 2025
-
Biosynthesis of Argolaphos Illuminates the Unusual Biochemical11 março 2025
você pode gostar
-
Wholesale Premium Blend Of Exotic Topshelf Flower Frostiez Certz11 março 2025
-
purple seer and green seer value|TikTok Search11 março 2025
-
The Strokes - You Only Live Once - Bass cover with tabs11 março 2025
-
Jesus The Agapegeek Blog11 março 2025
-
BFDIA 5b11 março 2025
-
Anime DVD Boku No Hero Academia Season 1-5 *English Dub* Ep.1-113 End + 3 Movies11 março 2025
-
Roblox Aery Nerf - How bad did it get? [Roblox Bedwars]11 março 2025
-
Brick Hill Heights - Apartments in South Portland, ME11 março 2025
-
números jogo, Educação ponto para ponto jogos para crianças11 março 2025
-
Five Nights at Freddy's 1 [CS2D] [Mods]11 março 2025