GPC2-CAR T cells tuned for low antigen density mediate potent
Por um escritor misterioso
Last updated 01 abril 2025

Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…

Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting

PDF) Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma

Frontiers CAR T Cell Therapy for Neuroblastoma

Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion - eBioMedicine

Vaccines, Free Full-Text

CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research

Strategies to enhance CAR-T persistence, Biomarker Research

CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice - ScienceDirect

Antigen density quantification of cell-surface immunotherapy targets by flow cytometry: Multi-antigen assay of neuroblastoma bone marrow metastasis - ScienceDirect

Membrane Proteome Array (MPA), Antibody Specificity Profiling

GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect

Strategies to enhance CAR-T persistence, Biomarker Research
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